Factors That Predict the Growth of Residual Nonfunctional Pituitary Adenomas: Correlations between Relapse and Cell Cycle Markers

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INVITED COMMENTARY Growth factors and human pituitary adenomas

In recent years, the demonstration that human pituitary adenomas are monoclonal provides further support for the existence of genomic mutations occurring in the progenitor cell that subsequently undergoes clonal expansion. All the molecules that physiologically control pituitary cell differentiation and growth may be potentially oncogenic as they may become the target of mutations or be altered...

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ژورنال

عنوان ژورنال: BioMed Research International

سال: 2018

ISSN: 2314-6133,2314-6141

DOI: 10.1155/2018/1876290